Tri-POC Tenofovir Dimer (>90%)
Stability Very Hygroscopic
Applications Tri-POC Tenofovir Dimer is a dimer of Tenofovir Disoproxil (T018505), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. It is also used in the preparation of phosphocitrate for the treatment of rheumatoid and osteoarthritis in the elderly.
References Turhanen, P. et al.: J. Org. Chem., 72, 1468 (2007);